I promise

"I promise, Suzy... Even if it takes the rest of my life." - Nancy G. Brinker, founder of Susan G. Komen for the Cure

What is Triple Negative Breast Cancer?

WHAT IS TRIPLE NEGATIVE BREAST CANCER?

Just in recent years, Triple Negative Breast Cancer has sparked interest in the news where instead of calling the tumor as ER-negative, PR-negative, and HER2-negative; researchers began using the shorthand term, "Triple Negative," dubbed the "new type" type of cancer. Being Triple Negative, you don't have a targeted therapy and that your only treatment option is chemotherapy.

Triple Negative is seen in about 15% of all breast cancers. Triple Negative is a very aggressive cancer that tends to strike younger women, pre-menopause, especially among African-American women and women who have BRCA1 mutations. The tumor tends to be fast growing and is less likely to show up on an annual mammogram. TN is more likely to metastasis early on; has a high rate of recurrence in the first 2-3 years from diagnosis and has a poorer prognosis than other types of breast cancer due to lack of specific, targeted treatment for TNBC.

Carpe diem

Seize Each new Day with Renewed Strength,
Believe in Yourself, Go forward with
Courage and faith
to face whatever Tomorrow may bring.

Chicks For Charity motto:

Enjoy life. Laugh a lot.
Work hard. Play hard.
Be thankful for our blessings.
Share the wisdom. Give back
.

Sunday, July 31, 2011

Toledo Mud Hens Komen Night, July 29, 2011



Me and my TNBC pink sister, Kim Youster 
who I met during our radiation treatments



The Toledo Mud Hens beat the Norfolk Tides, 5-2 at sold-out crowd of 10,300 during "Pink at the Park."  

Saturday, July 30, 2011

My 2nd, July 2011 Visit To North Carolina To See My Very Close TNBC Friend, Tracy

           
          Some people come into our lives
            and quickly go.
            Some stay for a while
            and leave footprints on our hearts.
            and we are never, ever the same.

Me, Tracy and Erica

Thursday, July 14, 2011

ProMedica Pink Glove Dance.Mov


Toledo, Ohio's version of Pink Glove Dance premiered today, 
Look for me towards the end of the video at 5:32, 
I'm wearing a black hat and blazer jacket... 


Keeping awareness in the forefront!


Tuesday, July 12, 2011

The SCAR Project, Breast Cancer Survivors Bares All For Awareness




Fashion Designer, David Jay shoots an exhibit of life size portraits of young women breast cancer survivors displaying their courage in raising awareness to early-onset breast cancer while raising funds for research and outreach programs. http://www.thescarproject.org/ (Click to link)

The SCAR Project: Breast Cancer Is Not a Pink ribbon.
(Volume I) Book containing portraits of young breast cancer survivors and their autobiographical account of their breast cancer journey. Available at amazon.com


“For these young women, having their portrait taken seems to represent their personal victory over this terrifying disease. It helps them reclaim their femininity, their sexuality, identity and power after having been robbed of such an important part of it. Through these simple pictures, they seem to gain some acceptance of what has happened to them and the strength to move forward with pride.”


Baring It All (The SCAR Project documentary) DVD available at amazon.com


Friday, July 8, 2011

Entinostat- Experimental Drug May Help Reprogram Tumor Cells To Respond To Hormone Therapy In Triple Negative Breast Cancer Patients


Triple Negative Breast Cancer cells
“We hope that Entinostat will make the tumor cells more sensitive to the drug anastrozole, causing the tumor to shrink or, at the very least, stop growing,” Dr. Chumsri says.
http://www.umm.edu/news/releases/triple-negative-breast-cancer.htm
(Click to link)





"The study will help researchers determine if an experimental drug, entinostat, can reprogram tumor cells to express a protein molecule called an estrogen receptor to make them sensitive to hormone therapy."





Wednesday, July 6, 2011

Nodal Status And Clinical Outcomes In A Large Cohort Of Patients With Triple-Negative Breast Cancer

Journal of Clinical Oncology, July 1, 2011
Conclusion: "In patients with TNBC, once there is evidence of lymph node metastasis, the prognosis may not be affected by the number of positive lymph nodes."
http://jco.ascopubs.org/content/29/19/2628.short?rss=1 
(click to link)

Tuesday, July 5, 2011

Mom... It's Cancer By Kathy Crews

momitscancer.com

Mom...It's Cancer: One Family, Two Women, Two Battles, Too Unimaginable! [Paperback]

Kathy Crews (Author)   momitscancer.com
Pg. 52 excerpt - " ... Tracy was learning more about triple-negative breast cancer, and  she was frightened by the number of unknowns about this cancer."...


Editorial Review by Peter Bonanno, Senior Pastor Grace Capital Church, Pembroke, N.H.
"Cancer...it's a word that many people fear and others avoid talking about. In this great story of living life with all of its disappointments, Kathy Crews shares the journey of discovering God's love as she walked through her own daughter's diagnosis and treatment for breast cancer. With much prayer and faith, Kathy helped her daughter and family press through, only to discover a few years later that she would be struck with the same disease. Somebody once said that everyone wants a miracle, but that no one wants to be in the position where they really need one. This is a book for those who need faith and who need a miracle. But don't expect there to be quick or easy answers, for as Kathy's story will help you to discover, it's through our most difficult circumstances that God can work the most good in our lives and cause us to produce fruit that is a blessing to many others." 

Sunday, July 3, 2011

Outcome Of Triple-Negative Breast Cancer Better With Lumpectomy Vs Mastectomy

Jun 16 , 2011 - "Breast-conserving therapy may provide better five-year locoregional control for women with triple-negative breast cancer than modified radical mastectomy without adjuvant radiation, according to a retrospective study from Canada."
http://www.medscape.com/viewarticle/744785?src=nl_topic
(Click to link)

‘Triple-Negative’ Breast Cancer Study May Help Guide Treatment Plan (06/30/11)


6/30/2011 - Vanderbilt-Ingram Cancer Center researchers have identified six subtypes of an aggressive and difficult-to-treat form of breast cancer, called “triple-negative breast cancer (TNBC).”


Not Just 1 disease but 6 subtypes of Triple Negative Breast Cancer and  identifying the different chemotherapies that they respond to:
  • BL1 and BL2 - These 2 "basal-like" types relates to cell cycle and DNA response genes and responds to the drug, Cisplatin.
  • M and MSL - These two "mesenchymal" types are driven by genes as it relates to cell differentiation and growth factor pathways that responds to the drug, Dasatinib and an experimental drug, NVP-BEZ235.
  • IM - A "immunomodulatory" type as it relates to immune system genes.
  • LAR - A "luminal" type relates to the "male" sex hormone, androgen signals and responds to the drug, Bicalutamide.

(Click to link)

Bay Area Researchers Look At Triple Negative Breast Cancer | abc7news.com


6/23/2011- TNBC survivor, Louisa Gloger  started a non-profit called Triple Step raising more than a quarter of a million dollars.
http://www.triplesteptowardthecure.org - Understanding Triple Negative Breast Cancer











Rare Form Of Breast Cancer Targets The Young « CBS Chicago

3/16/2011- "If you’re in your 20′s or 30′s you’re more susceptible and if you’re a black woman, you face a higher risk. It’s a type of breast cancer researchers know little about."
 Rare Form Of Breast Cancer Targets The Young « CBS Chicago (Click link to full story)

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