TGF-b Inhibitors Needed to Target Stem-Like Cancer Cells In Triple Negative Breast Cancer

"A new study by Vanderbilt-Ingram Cancer Center investigators suggests drugs that block or inhibit the TGF-b signaling pathway in cancer cells enhance the effect of chemotherapy and may prevent recurrences of treatment-resistant TNBC..."
...Chemotherapy drugs are designed to attack fast-dividing cancer cells. Recent research suggests that after an initial response to chemotherapy a small population of slower growing cells known as cancer stem-like cells (CSCs) survives and regenerates, causing metastatic tumor recurrences...
http://news.vanderbilt.edu/2013/03/breast-cancer-study-explores-therapy-to-slow-recurrence/
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