Researchers Link Protein With Breast Cancer's Spread to the Brain

"Furthermore, the team found breast tumors that expressed alphaB-crystallin were more likely to be triple-negative breast cancers - an aggressive type of cancer, which lacks three receptors (estrogen receptor, progesterone receptor and HER-2) expressed in other types of breast cancer. Triple-negative breast cancers are known to have a high incidence of brain metastasis."

“Our findings suggest that alphaB-crystallin may contribute to the tendency of triple-negative breast cancers to metastasize to the brain and to their poor prognosis,” said Cryns. Yet, he cautioned these findings need to be validated in additional studies."

http://www.med.wisc.edu/news-events/uw-madison-researchers-link-protein-with-breast-cancers-spread-to-the-brain/42519  (Click link to complete story)