What is Triple Negative Breast Cancer?
WHAT IS TRIPLE NEGATIVE BREAST CANCER?
Just in recent years, Triple Negative Breast Cancer has sparked interest in the news where instead of calling the tumor as ER-negative, PR-negative, and HER2-negative; researchers began using the shorthand term, "Triple Negative," dubbed the "new type" type of cancer. Being Triple Negative, you don't have a targeted therapy and that your only treatment option is chemotherapy.Triple Negative is seen in about 15% of all breast cancers. Triple Negative is a very aggressive cancer that tends to strike younger women, pre-menopause, especially among African-American women and women who have BRCA1 mutations. The tumor tends to be fast growing and is less likely to show up on an annual mammogram. TN is more likely to metastasis early on; has a high rate of recurrence in the first 2-3 years from diagnosis and has a poorer prognosis than other types of breast cancer due to lack of specific, targeted treatment for TNBC.
Seize Each new Day with Renewed Strength,Believe in Yourself, Go forward withCourage and faithto face whatever Tomorrow may bring.
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Sunday, July 31, 2011
Saturday, July 30, 2011
Wednesday, July 27, 2011
Anti-Cancer Drug, ABT-737 Combined With Chemotherapy Improves Tumor Response In Triple Negative Breast Cancers
Thursday, July 14, 2011
Tuesday, July 12, 2011
Fashion Designer, David Jay shoots an exhibit of life size portraits of young women breast cancer survivors displaying their courage in raising awareness to early-onset breast cancer while raising funds for research and outreach programs. http://www.thescarproject.org/ (Click to link)
Baring It All (The SCAR Project documentary) DVD available at amazon.com
Friday, July 8, 2011
Entinostat- Experimental Drug May Help Reprogram Tumor Cells To Respond To Hormone Therapy In Triple Negative Breast Cancer Patients
|Triple Negative Breast Cancer cells|
(Click to link)
"The study will help researchers determine if an experimental drug, entinostat, can reprogram tumor cells to express a protein molecule called an estrogen receptor to make them sensitive to hormone therapy."
Wednesday, July 6, 2011
Conclusion: "In patients with TNBC, once there is evidence of lymph node metastasis, the prognosis may not be affected by the number of positive lymph nodes."
(click to link)
Tuesday, July 5, 2011
Mom...It's Cancer: One Family, Two Women, Two Battles, Too Unimaginable! [Paperback]Kathy Crews (Author) momitscancer.com
Pg. 52 excerpt - " ... Tracy was learning more about triple-negative breast cancer, and she was frightened by the number of unknowns about this cancer."...
Editorial Review by Peter Bonanno, Senior Pastor Grace Capital Church, Pembroke, N.H.
"Cancer...it's a word that many people fear and others avoid talking about. In this great story of living life with all of its disappointments, Kathy Crews shares the journey of discovering God's love as she walked through her own daughter's diagnosis and treatment for breast cancer. With much prayer and faith, Kathy helped her daughter and family press through, only to discover a few years later that she would be struck with the same disease. Somebody once said that everyone wants a miracle, but that no one wants to be in the position where they really need one. This is a book for those who need faith and who need a miracle. But don't expect there to be quick or easy answers, for as Kathy's story will help you to discover, it's through our most difficult circumstances that God can work the most good in our lives and cause us to produce fruit that is a blessing to many others."
Monday, July 4, 2011
Download The NEW Brochure - State-Of-The-Art Treatment For Triple Negative Breast Cancer: Talking With The Experts Oncology Presented
Sunday, July 3, 2011
(Click to link)
Not Just 1 disease but 6 subtypes of Triple Negative Breast Cancer and identifying the different chemotherapies that they respond to:
- BL1 and BL2 - These 2 "basal-like" types relates to cell cycle and DNA response genes and responds to the drug, Cisplatin.
- M and MSL - These two "mesenchymal" types are driven by genes as it relates to cell differentiation and growth factor pathways that responds to the drug, Dasatinib and an experimental drug, NVP-BEZ235.
- IM - A "immunomodulatory" type as it relates to immune system genes.
- LAR - A "luminal" type relates to the "male" sex hormone, androgen signals and responds to the drug, Bicalutamide.
http://www.triplesteptowardthecure.org - Understanding Triple Negative Breast Cancer
Rare Form Of Breast Cancer Targets The Young « CBS Chicago (Click link to full story)
My Favorite Breast Cancer Sites
- Triple Negative Breast Cancer Foundation
- Young Survival Coalition
- Living Beyond Breast Cancer
- Susan G. Komen for the Cure
- 1 Up on Cancer
- Triple Step Toward The Cure
- American Cancer Society Making Strides Against Breast Cancer
- The Victory Center
- Renee's Survivor Shop
- Relay for Life
- The SCAR Project
- CURE makes cancer understandable
- BREASTCANCER.ORG Discussions Boards
- Jennifer Griffin's Blog
- Positives about Negative
- National Breast Cancer Foundation
- Breast Cancer
- Breast Cancer Fund
- The Breast Cancer Site
- Food for Breast Cancer
- Breast Cancer Awareness Body Painting Project
- Ford Warriors in Pink
- Feel Your Boobies