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"I promise, Suzy... Even if it takes the rest of my life." - Nancy G. Brinker, founder of Susan G. Komen for the Cure

What is Triple Negative Breast Cancer?

WHAT IS TRIPLE NEGATIVE BREAST CANCER?

Just in recent years, Triple Negative Breast Cancer has sparked interest in the news where instead of calling the tumor as ER-negative, PR-negative, and HER2-negative; researchers began using the shorthand term, "Triple Negative," dubbed the "new type" type of cancer. Being Triple Negative, you don't have a targeted therapy and that your only treatment option is chemotherapy.

Triple Negative is seen in about 15% of all breast cancers. Triple Negative is a very aggressive cancer that tends to strike younger women, pre-menopause, especially among African-American women and women who have BRCA1 mutations. The tumor tends to be fast growing and is less likely to show up on an annual mammogram. TN is more likely to metastasis early on; has a high rate of recurrence in the first 2-3 years from diagnosis and has a poorer prognosis than other types of breast cancer due to lack of specific, targeted treatment for TNBC.

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Seize Each new Day with Renewed Strength,
Believe in Yourself, Go forward with
Courage and faith
to face whatever Tomorrow may bring.

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Wednesday, September 28, 2011

Test Could Detect Breast Cancers Earlier in Young, High-risk African-American Women

In a recent study, it suggests that testing on how the body's cells consume and breakdown sugar that activate cancerous insulin signaling pathways in Triple Negative Breast Cancer, may give researchers insight in detecting and preventing this cancer.  These studies revealed that young women that are prone to develop gestational diabetes and prediabetes, where the body produces increased sugar, may fuel precancerous cells, turning them into cancerous cells. This condition can be controlled through exercise, weight loss and diabetes drugs.

“One of the hallmarks of really aggressive cancers is that they start taking sugar, breaking it down and turning it into energy,” she said. “It becomes their primary source of energy and that allows the cancer cells to grow rapidly.”
http://www.aacr.org/home/public--media/aacr-in-the-news.aspx?d=2457  
(Click link for full story)

2 comments:

  1. interesting blog. It would be great if you can provide more details about it. Thanks you



    Gestational Diabetes

    ReplyDelete
  2. kousalya, click link to full story, Thank you.

    ReplyDelete

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