I promise

"I promise, Suzy... Even if it takes the rest of my life." - Nancy G. Brinker, founder of Susan G. Komen for the Cure

What is Triple Negative Breast Cancer?


Just in recent years, Triple Negative Breast Cancer has sparked interest in the news where instead of calling the tumor as ER-negative, PR-negative, and HER2-negative; researchers began using the shorthand term, "Triple Negative," dubbed the "new type" type of cancer. Being Triple Negative, you don't have a targeted therapy and that your only treatment option is chemotherapy.

Triple Negative is seen in about 15% of all breast cancers. Triple Negative is a very aggressive cancer that tends to strike younger women, pre-menopause, especially among African-American women and women who have BRCA1 mutations. The tumor tends to be fast growing and is less likely to show up on an annual mammogram. TN is more likely to metastasis early on; has a high rate of recurrence in the first 2-3 years from diagnosis and has a poorer prognosis than other types of breast cancer due to lack of specific, targeted treatment for TNBC.

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Seize Each new Day with Renewed Strength,
Believe in Yourself, Go forward with
Courage and faith
to face whatever Tomorrow may bring.

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Enjoy life. Laugh a lot.
Work hard. Play hard.
Be thankful for our blessings.
Share the wisdom. Give back

Monday, July 7, 2014

Triple Negative Breast Cancer, an Inflammation-Associated Cancer?

March 5, 2014 Press Release

"In this study, using a mouse model for human breast cancer, we showed that TNBC's characteristics --  rapid tumor growth and metastasis -- is heavily dependent upon and fueled by markedly evaluated transcriptional activation of pro-inflammatory cytokines and chemokines," said Dr. Zhou.  "Using a small molecule to target that gene transcriptional machinery, we further uncovered and validated a drug target for potential new treatment of TNBC, which account for more than 170,000 new breast cancers annually and which disproportionately affects women of African and Hispanic descent.  While much more research needs to be done, our findings are very promising and give us hope in the overall war against breast cancer."
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  1. This quote "...we further uncovered and validated a drug target for potential new treatment of TNBC..." is so encouraging! Thanks, Mel :)


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